Design and Modeling of Magnetoelectric Micro-Particles for Neuromodulation

This paper presents a novel approach to neural stimulation using magnetoelectric microparticles (MEMP), potentially transforming biostimulation methods. We employ multi-physics modeling to integrate MEMPs into a simulation framework, focusing on designing spherical core-shell structures. These structures exploit resonant modes and the nonlinearity of magnetostrictive materials to amplify deformation under high-frequency magnetic fields. This process effectively down-converts remotely applied high-frequency signals into low-frequency deformations, crucial for neural stimulation. The interaction between the magnetostrictive core and the piezoelectric shell, particularly under resonance, enhances mechanical-to-electrical energy conversion, elevating bio-stimulation capabilities. Our findings suggest a path towards more efficient, targeted, and minimally invasive neural stimulation, with implications for advancing biomédical engineering and neuroscience.