TY - GEN
T1 - Design of Nano-Robots for Exposing Cancer Cells
AU - Dolev, Shlomi
AU - Rosenblit, Michael
AU - Narayanan, Ram Prasadh
N1 - Funding Information:
We thank the Lynne and William Frankel Center for Computer Science, the Rita Altura Trust Chair in Computer Science, the Kreitman School of Advanced Graduate Studies, Ben-Gurion University of the Negev for their support to this work. This research was also supported by a grant from the Ministry of Science & Technology, Israel & the Japan Science and Technology Agency (JST), Japan. We also thank Prof. Zeev Zalevsky from Bar-Ilan University for his useful comments and assistance.
Publisher Copyright:
© 2018 IEEE.
PY - 2019/1/24
Y1 - 2019/1/24
N2 - A proof-of-concept design of a nano-robot which can navigate, detect cancer cells in blood and actuate the release of drugs is discussed. The nano-robot was designed with blood energy harvesting capability and accumulation of electricity in a capacitor, which forms the main body of the nano-robot. Glucose hunger-based cancer detectors immobilized on the nano-robot, reduces its electrical resistance, when attached to a cancer cell. This mechanism, in-turn, allows electric current to activate a nano-electrical-mechanical (NEM) relay (mechanical transistor) to break the ceiling, exposing a drug identified by the immune system for cell elimination. This concept is in line with the effort to design an autonomous computational nano-robot for in-vivo medical diagnosis and treatment. A collective system of electrical manipulation, bio-detection and NEM actuation can visualize the programmability in the nano matters. The concept can also be considered as a step to bridge the gap between theoretical swarming/navigation techniques and a computational hardware for plausible implementation of the theory.
AB - A proof-of-concept design of a nano-robot which can navigate, detect cancer cells in blood and actuate the release of drugs is discussed. The nano-robot was designed with blood energy harvesting capability and accumulation of electricity in a capacitor, which forms the main body of the nano-robot. Glucose hunger-based cancer detectors immobilized on the nano-robot, reduces its electrical resistance, when attached to a cancer cell. This mechanism, in-turn, allows electric current to activate a nano-electrical-mechanical (NEM) relay (mechanical transistor) to break the ceiling, exposing a drug identified by the immune system for cell elimination. This concept is in line with the effort to design an autonomous computational nano-robot for in-vivo medical diagnosis and treatment. A collective system of electrical manipulation, bio-detection and NEM actuation can visualize the programmability in the nano matters. The concept can also be considered as a step to bridge the gap between theoretical swarming/navigation techniques and a computational hardware for plausible implementation of the theory.
UR - http://www.scopus.com/inward/record.url?scp=85062277077&partnerID=8YFLogxK
U2 - 10.1109/NANO.2018.8626359
DO - 10.1109/NANO.2018.8626359
M3 - Conference contribution
AN - SCOPUS:85062277077
T3 - Proceedings of the IEEE Conference on Nanotechnology
BT - 18th International Conference on Nanotechnology, NANO 2018
PB - IEEE Computer Society
T2 - 18th International Conference on Nanotechnology, NANO 2018
Y2 - 23 July 2018 through 26 July 2018
ER -
