Abstract
RNA switches respond to specific ligands to control gene expression. They are widely used in synthetic biology applications and hold potential for future RNA-based therapeutic breakthroughs. However, the crux is their precise design. Here, we will discuss how inverse-RNA-folding could be utilized for the accurate design of RNA switches.
Original language | English |
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Pages (from-to) | 517-521 |
Number of pages | 5 |
Journal | Trends in Biotechnology |
Volume | 42 |
Issue number | 5 |
DOIs | |
State | Published - 1 May 2024 |
Keywords
- RNA switch
- RNA-based therapeutics
- inverse-RNA-folding
- riboswitch
- ribozyme
- synthetic biology
ASJC Scopus subject areas
- Biotechnology
- Bioengineering