Detection of varicella-zoster virus-specific iga antibodies in varicella and zoster patients and in healthy adults of various ages by solid-phase radioimmunoassay

E. Levy, B. Mosovitz, M. Friedman, I. Sarov

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The varicella-zoster virus(VZV)-specific serum immunoglobulin A (IgA) response was studied in varicella and zoster patients and in healthy adults of various ages by a sensitive solid-phase radioimmunoassay technique. Significant rises in VZV-specific IgA titer were found for both varicella and zoster patients, while VZV-specific IgA was also detected in > 90% of healthy adults but at lower titers. No significant decrease in VZV-specific IgA titer with increasing age was found. The role of humoral versus cell-mediated immunity in VZV reactivation is discussed.

Original languageEnglish
Pages (from-to)123-128
Number of pages6
JournalIntervirology
Volume20
Issue number2-3
DOIs
StatePublished - 1 Jan 1983
Externally publishedYes

Keywords

  • IgA antibodies
  • Radioimmunoassay
  • Varicella
  • Zoster

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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