Development of spinal cord on a microfludic chip

Sareen Dhruv (Inventor), S Kerns Jordan (Inventor), Wen Norman (Inventor), Lucchesi Carol (Inventor), Hinojosa Chris (Inventor), Fraser Jacob (Inventor), Hamilton Geraldine (Inventor), Vatine Gad (Inventor), Sances Samuel (Inventor), Svendsen Clive (Inventor), Levner Daniel (Inventor)

Research output: Patent


The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.

Original languageEnglish
Patent numberGB2568446
IPCC12N 15/ 85 A I
Priority date29/08/17
StatePublished - 15 May 2019


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