Development of spinal cord on a microfluidic chip

Jordan Kerns (Inventor), Norman Wen (Inventor), Carol Lucchesi (Inventor), Christopher Hinojosa (Inventor), Jacob Fraser (Inventor), Geraldine Hamilton (Inventor), Gad Vatine (Inventor), Sam Sances (Inventor), Clive Svendsen (Inventor), Daniel Levner (Inventor)

Research output: Patent

Abstract

The invention relates to culturing brain endothelial cells, and optionally astrocytes and neurons in a fluidic device under conditions whereby the cells mimic the structure and function of the blood brain barrier. Culture of such cells in a microfluidic device, whether alone or in combination with other cells, drives maturation and/or differentiation further than existing systems.
Original languageEnglish
Patent numberUS2018057788
StatePublished - 1 Mar 2018

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