Different AIS triplets: Different mortality predictions in identical ISS and NISS

Limor Aharonson-Daniel, Adi Giveon, Michael Stein, Kobi Peleg, R. Alficci, J. Jeroukhimov, Y. Klein, Y. Kluger, M. Michaelson, A. Rivkind, G. Shaked, D. Simon, D. Soffer, M. Stein

    Research output: Contribution to journalArticlepeer-review

    49 Scopus citations


    BACKGROUND: Previous studies demonstrated different mortality predictions for identical Injury Severity Scores (ISS) from different Abbreviated Injury Scale (AIS) triplets. This study elaborates in both scope and volume producing results of a larger magnitude, applicable to specific injury subgroups of blunt or penetrating, taumatic brain injury, various age groups, and replicated on NISS. METHODS: All patients hospitalized after trauma at 10 hospitals, with ISS/NISS (new ISS) generated by two AIS triplets, excluding patients with isolated minor or moderate injuries to a single body region were studied. Patients were separated into two groups based on the different triplets. Inpatient-mortality rates were calculated for each triplet group. Odds ratios were calculated to estimate the risk of dying in one triplet group as compared with the other. The χ test determined whether the difference in mortality rate between the two groups was significantly different. Differences were further explored for various subgroups. RESULTS: There were 35,827 patients who had ISS/NISS scores generated by two different AIS triplets. Significant differences in death rates were noted between triplet groups forming identical ISS/NISS. Odds ratio for being in the second group (always containing the higher AIS score) ranged from 2.3 to 7.4. CONCLUSIONS: ISS and NISS that are formed by different AIS triplets have significantly different inpatient-mortality rates. The triplet with the higher AIS score has higher inpatient-mortality rates, overall and in several sub-populations of varying vulnerability. The comparison of populations and the interpretation of ISS/NISS based outcome data should take this important information into account and the components of AIS triplets creating each ISS and NISS should be reported.

    Original languageEnglish
    Pages (from-to)711-717
    Number of pages7
    JournalJournal of Trauma and Acute Care Surgery
    Issue number3
    StatePublished - 1 Sep 2006


    • Injury Severity Score
    • Inpatient mortality
    • Methodology
    • Trauma

    ASJC Scopus subject areas

    • Surgery
    • Critical Care and Intensive Care Medicine


    Dive into the research topics of 'Different AIS triplets: Different mortality predictions in identical ISS and NISS'. Together they form a unique fingerprint.

    Cite this