Differential uptake of myo-inositol in vivo into rat brain areas

Yardena Patishi, Beate Lubrich, Mathias Berger, Ora Kofman, Dietrich Van Calker, R. H. Belmaker

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Oral inositol has been reported to have antidepressant and antipanic properties in humans. Inositol enters the brain poorly and high doses are required. Natural uptake processes and specific transporters are involved. We here report that intraperitoneally administered inositol is taken up differently by various brain areas and that brain areas have different baseline inositol levels. These effects could be important in understanding the differential effects of lithium-induced lowering of inositol and of behavioral effects of exogenous inositol.

Original languageEnglish
Pages (from-to)73-75
Number of pages3
JournalEuropean Neuropsychopharmacology
Issue number1
StatePublished - 1 Jan 1996


  • Brain areas
  • Inositol
  • Uptake

ASJC Scopus subject areas

  • Pharmacology
  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Pharmacology (medical)


Dive into the research topics of 'Differential uptake of myo-inositol in vivo into rat brain areas'. Together they form a unique fingerprint.

Cite this