Differentiated thyroid cancer with epiphora: Detection of nasolacrimal duct obstruction on I-131 SPECT/CT

Salem Yuoness, Irina Rachinsky, Albert A. Driedger, Tarik Z. Belhocine

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Chronic excess tearing or epiphora is seen in differentiated thyroid cancer patients who have received multiple doses of I-131 therapy. A 25-year-old woman with a papillary thyroid cancer received 6 doses of I-131 (±37GBq) for I-131-avid lung metastases. The patient underwent a diagnostic I-131 whole-body scan plus SPECT/CT for a borderline thyroglobulin. I-131 whole-body scan demonstrated a right periorbital focus as shown in Figure 1, which was precisely localized on SPECT/CT at the right proximal nasolacrimal duct as shown in Figure 2. Dacryoscintigraphy documented a right high-grade obstruction as shown in Figures 3 and 4. The patient underwent a right dacryocystorhinostomy with a Crawford tube insertion. SPECT/CT allows anatofunctional definition of pathophysiological I-131 uptake patterns.

Original languageEnglish
Pages (from-to)1149-1152
Number of pages4
JournalClinical Nuclear Medicine
Volume36
Issue number12
DOIs
StatePublished - 1 Dec 2011
Externally publishedYes

Keywords

  • I-131 therapy
  • SPECT/low-dose CT
  • dacryoscintigraphy
  • differentiated thyroid cancer
  • nasolacrimal duct obstruction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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