Diffusion kinetics of the glucose/glucose oxidase system in swift heavy ion track-based biosensors

Dietmar Fink, Jiri Vacik, V. Hnatowicz, G. Muñoz Hernandez, H. Garcia Arrelano, Lital Alfonta, Arik Kiv

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


For understanding of the diffusion kinetics and their optimization in swift heavy ion track-based biosensors, recently a diffusion simulation was performed. This simulation aimed at yielding the degree of enrichment of the enzymatic reaction products in the highly confined space of the etched ion tracks. A bunch of curves was obtained for the description of such sensors that depend only on the ratio of the diffusion coefficient of the products to that of the analyte within the tracks. As hitherto none of these two diffusion coefficients is accurately known, the present work was undertaken. The results of this paper allow one to quantify the previous simulation and hence yield realistic predictions of glucose-based biosensors. At this occasion, also the influence of the etched track radius on the diffusion coefficients was measured and compared with earlier prediction.

Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalNuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms
StatePublished - 1 May 2017


  • Biosensor
  • Diffusion
  • Enzyme
  • Etched ion tracks
  • Polymer
  • Track radius

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation


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