Directed evolution of a soluble human DR3 receptor for the inhibition of TL1A induced cytokine secretion

Keyphrases

• Autoimmune Disease 100%
• Directed Evolution 100%
• Cytokine Secretion 100%
• Drug Candidates 33%
• Cell-based 33%
• Therapeutic Approaches 33%
• Inflammatory Bowel Disease 33%
• Inflammation 33%
• Surface Expression 33%
• Induced Cell Death 33%
• Rheumatoid Arthritis 33%
• CD4+ T Cells 33%
• Post-translational Modification 33%
• Asthma 33%
• Binding Affinity 33%
• TF-1 Cells 33%
• Cell Secretion 33%
• Yeast Surface Display 33%
• TNF Superfamily 33%
• Cysteine Content 33%
• Binding Stability 33%
• Mammalian Cell Lines 33%

Immunology and Microbiology

• Tumor Necrosis Factor 100%
• Cytokine Release 100%
• Autoimmune Disease 42%
• Cell Line 14%
• Surface Property 14%
• Cytokine 14%
• Inflammatory Bowel Disease 14%
• Cell Death 14%
• T-Helper Cell 14%
• Protein Processing 14%
• Binding Affinity 14%
• Asthma 14%
• Inflammatory Arthritis 14%
• Cellular Secretion 14%
• TF-1 Cell Line 14%