Discovery of novel agonists and antagonists of the free fatty acid receptor 1 (FFAR1) using virtual screening

Keyphrases

• Virtual Screening 100%
• Free Fatty Acid Receptors 100%
• Docking Studies 50%
• Two Dimensional 25%
• Three-dimensional (3D) 25%
• Amino Acids 25%
• Mutagenesis 25%
• Ligand Binding Site 25%
• G Protein-coupled Receptor 25%
• New Ligand 25%
• Type 2 Diabetes Prevention 25%
• Site-directed mutagenesis 25%
• Partial Agonist 25%
• Ligand-receptor Interaction 25%
• Mutagenesis Studies 25%
• Full Agonist 25%
• GPR40 25%
• Dimensional Similarity 25%
• Pharmacophore Query 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Virtual Screening 100%
• G Protein Coupled Receptor 40 100%
• Receptor 50%
• Amino Acid 25%
• Non Insulin Dependent Diabetes Mellitus 25%
• Mutagenesis 25%
• G Protein Coupled Receptor 25%
• Binding Site 25%
• Partial Agonist 25%
• Site-Directed Mutagenesis 25%

Immunology and Microbiology

• Agonist 100%
• Mutagenesis 25%
• Binding Site 25%
• Ligand Binding 25%
• Site Directed Mutagenesis 25%
• Pharmacophore 25%