Disseminated mucormycosis masquerading as rejection early after orthotopic heart transplantation

Lindsay Margoles, David DeNofrio, Ayan R. Patel, Yoav Golan, Amanda R. Vest, Knarik Arkun, Helen W. Boucher, Michael S. Kiernan, Jenica N. Upshaw

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Mucorales organisms are an uncommon cause of invasive fungal infections after solid organ transplantation but are associated with great morbidity and mortality. We report a fatal case of disseminated Cunninghamella infection early after heart transplantation. The patient developed graft dysfunction and elevated markers of myocyte injury and autopsy revealed fulminant fungal myocarditis. This case highlights the need for a high index of suspicion in immunocompromised patients who are not improving with standard antimicrobial therapy.

Original languageEnglish
Article numbere12820
JournalTransplant Infectious Disease
Issue number1
StatePublished - 1 Feb 2018
Externally publishedYes


  • fungal infections
  • heart transplantation
  • mucormycosis

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation


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