Double functionalization of carbon nanotubes with purine and pyrimidine derivatives

Prabhpreet Singh, Cécilia Ménard-Moyon, Alessia Battigelli, Francesca Maria Toma, Jesus Raya, Jitendra Kumar, Nagapradeep Nidamanuri, Sandeep Verma, Alberto Bianco

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Herein, we have developed a synthetic strategy for the covalent double functionalization of single-walled carbon nanotubes (SWCNTs) with a combination of purine-pyrimidine and purine-purine nucleobase systems. The nucleobases were introduced on the sidewall of oxidized SWCNTs through 1,3-dipolar cycloaddition and by amidation of the carboxylic acids located at the tips and defect sites of the nanotubes. The new nanohybrids were characterized by transmission electron microscopy, thermogravimetric analysis, FTIR and Raman spectroscopy, magic-angle spinning NMR spectroscopy, and Kaiser test. The nucleobase/SWCNT conjugates can be envisaged for the modulation of the interactions with nucleic acids by means of base pairing, thereby opening new possibilities in the development of DNA/CNT nanobioconjugates.

Original languageEnglish
Pages (from-to)1472-1481
Number of pages10
JournalChemistry - An Asian Journal
Volume8
Issue number7
DOIs
StatePublished - 1 Jul 2013
Externally publishedYes

Keywords

  • carbon nanotubes
  • functionalization
  • nanostructures
  • nucleobases
  • self-assembly

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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