Dynamic Covalent Template-Guided Screen for Nucleic Acid-Targeting Agents

Keyphrases

• Aldehydes 33%
• Amines 33%
• DNA Repeats 33%
• Dual-target Inhibitor 33%
• Dynamic Covalent 100%
• Dynamic Covalent Chemistry 33%
• Dynamic Covalent Libraries 33%
• Expanded DNA 33%
• Huntington's Disease 66%
• IC50 Value 33%
• In Situ 33%
• Inhibitory Concentration 33%
• Matrix-assisted Laser Desorption Ionization Mass Spectrometry 33%
• Multivalent 33%
• Myotonic Dystrophy 33%
• Nucleic Acid Targets 100%
• Repeat Sequence 33%
• Screening Approach 33%
• Target-guided 33%
• Targeted Agents 100%
• Template-guided 100%
• Trinucleotide Repeat Diseases 33%

Biochemistry, Genetics and Molecular Biology

• DNA Template 100%
• IC50 33%
• Inhibitory Concentration 33%
• Mass Spectrometry 33%
• Matrix-Assisted Laser Desorption/Ionization 33%
• Nucleic Acid 100%
• Repeated Sequence (DNA) 33%
• Transcription 33%
• Trinucleotide Repeat Expansion 33%

Chemistry

• Deoxyribonucleic Acid 33%
• Dynamic Covalent Chemistry 33%
• IC50 33%
• Inhibitory Concentration 33%
• Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry 33%
• Nucleic Acid 100%
• Primary Structure 33%