Effect of 1-Propanol on the Activity of Intestinal Proteolytic Enzymes of the European Sea Bass Dicentrarchus labrax

The effect of 1-propanol and aliphatic alcohols on intestinal proteolytic and peptidase activities of the European sea bass Dicentrarchus labrax was examined in vitro. Results show that 1-propanol has a definite enhancing effect on the activity of trypsin and carboxypeptidase B as well as on the total proteolytic activity when tested with casein. Other intestinal enzymes were inhibited to various extents by 1-propanol. Effects of other aliphatic alcohols (e.g., butanols, 2-propanol, ethanol, and methanol) were tested as well. Results show that the less polar alcohols brought about the highest amplification of trypsin activit.