Effect of bovine growth hormone administration on the pattern of thymic involution in mice

Y. Bar-Dayan, M. Small

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Age-related decline of the thymus in mice was reversed by repeated injections of bovine growth hormone. After hormone administration that was begun at 5, 8, or 11.5 months of age, the cortical volume fraction (Vc), cortical/medullary ratio (C/M) and thymocyte numbers found were in the range obtained with younger mice. Growth hormone injection reduced the slope of the curves for Vc and C/M as a function of age, indicating a slowing down of the involution process.

Original languageEnglish
Pages (from-to)95-101
Number of pages7
JournalThymus
Volume23
Issue number2
StatePublished - 1 Dec 1994
Externally publishedYes

Keywords

  • Growth hormone
  • Thymic involution

Fingerprint

Dive into the research topics of 'Effect of bovine growth hormone administration on the pattern of thymic involution in mice'. Together they form a unique fingerprint.

Cite this