Effect of cannabinoids on the activity of monoamine oxidase in normal human platelets

M. Mazor, A. Dvilansky, M. Aharon, Z. Lazarovitz, I. Nathan

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Platelet MAO activity was affected by preincubation with cannabinoid derivatives in vitro. The psycho-active derivative Δ1-THC inhibited MAO activity in platelets to an extent varying according to its concentration while CBD and (+ Δ6-THC had no inhibitory effect. (-) δ6-THC, which is a minor psychomimetic component, had less inhibitory effect on MAO activity than Δ1-THC. However, (-) DMH Δ6-THC revealed no attenuation effect on MAO inspite of its well-known psychomimetic activity.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalArchives of Physiology and Biochemistry
Volume90
Issue number1
DOIs
StatePublished - 1 Jan 1982

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

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