Effect of Ca2+ Binding by EGTA on Renin Release in the Isolated Perfused Rabbit Kidney

Reuven J. Viskoper; Sheldon Rosenfeld; Morton H. Maxwell; Jose de Lima; Andrei N. Lupu; Joseph B. Rosenfeld

doi:10.3181/00379727-152-39409

Effect of Ca²⁺ Binding by EGTA on Renin Release in the Isolated Perfused Rabbit Kidney

Reuven J. Viskoper, Sheldon Rosenfeld, Morton H. Maxwell, Jose de Lima, Andrei N. Lupu, Joseph B. Rosenfeld

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

In the isolated, perfused rabbit kidney, binding of ionized calcium by EGTA did not affect the increased renin release secondary to two well-known stimuli, theophylline and isoproterenol. These results indicate that Ca²⁺ is not a major factor in the intrarenal regulation of renin secretion.

Original language	English
Pages (from-to)	415-418
Number of pages	4
Journal	Experimental Biology and Medicine
Volume	152
Issue number	3
DOIs	https://doi.org/10.3181/00379727-152-39409
State	Published - 1 Jan 1976
Externally published	Yes

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Effect of Ca2+ Binding by EGTA on Renin Release in the Isolated Perfused Rabbit Kidney",

abstract = "In the isolated, perfused rabbit kidney, binding of ionized calcium by EGTA did not affect the increased renin release secondary to two well-known stimuli, theophylline and isoproterenol. These results indicate that Ca2+ is not a major factor in the intrarenal regulation of renin secretion.",

author = "Viskoper, {Reuven J.} and Sheldon Rosenfeld and Maxwell, {Morton H.} and Lima, {Jose de} and Lupu, {Andrei N.} and Rosenfeld, {Joseph B.}",

note = "Funding Information: This study has been supported by Grant No. 415 IG (7) and (8) from the American Heart Association-Greater Los Angeles Affiliate, and the University Medical Research Foundation, and by U.S. Public Health Service Grant No. HL 04868. 2 ",

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AU - Viskoper, Reuven J.

AU - Rosenfeld, Sheldon

AU - Maxwell, Morton H.

AU - Lima, Jose de

AU - Lupu, Andrei N.

AU - Rosenfeld, Joseph B.

N1 - Funding Information: This study has been supported by Grant No. 415 IG (7) and (8) from the American Heart Association-Greater Los Angeles Affiliate, and the University Medical Research Foundation, and by U.S. Public Health Service Grant No. HL 04868. 2

PY - 1976/1/1

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N2 - In the isolated, perfused rabbit kidney, binding of ionized calcium by EGTA did not affect the increased renin release secondary to two well-known stimuli, theophylline and isoproterenol. These results indicate that Ca2+ is not a major factor in the intrarenal regulation of renin secretion.

AB - In the isolated, perfused rabbit kidney, binding of ionized calcium by EGTA did not affect the increased renin release secondary to two well-known stimuli, theophylline and isoproterenol. These results indicate that Ca2+ is not a major factor in the intrarenal regulation of renin secretion.

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JO - Experimental Biology and Medicine

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Effect of Ca²⁺ Binding by EGTA on Renin Release in the Isolated Perfused Rabbit Kidney

Abstract

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