Effect of lysine vasopressin in depressed patients on mood and 24-hour rhythm of growth hormone, cortisol, melatonin and prolactin

Joseph Zohar; Dov Drummer; E. D. Edelstein; Nurit Kaiser; Robert H. Belmaker; Isaac Nir

doi:10.1016/0306-4530(85)90004-6

Effect of lysine vasopressin in depressed patients on mood and 24-hour rhythm of growth hormone, cortisol, melatonin and prolactin

Joseph Zohar, Dov Drummer, E. D. Edelstein, Nurit Kaiser, Robert H. Belmaker, Isaac Nir

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Lysine-8-vasopressin (LVP) for 10 days and in doses up to 13.5 LVP units did not significantly alter the Hamilton Depression Rating Scale scores of 12 severely depressed, treatment-resistant patients who were evaluated in a double-blind crossover study. The 24-h rhythms of melatonin, cortisol, growth hormone and prolactin appeared remarkably stable over the course of repeated measurement. LVP administration did not affect these 24-h rhythms.

Original language	English
Pages (from-to)	273-279
Number of pages	7
Journal	Psychoneuroendocrinology
Volume	10
Issue number	3
DOIs	https://doi.org/10.1016/0306-4530(85)90004-6
State	Published - 1 Jan 1985
Externally published	Yes

Keywords

24-h rhythm
Lysine vasopressin
cortisol
growth hormone
melatonin
prolactin
resistant depression

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Psychiatry and Mental health
Biological Psychiatry

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10.1016/0306-4530(85)90004-6

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title = "Effect of lysine vasopressin in depressed patients on mood and 24-hour rhythm of growth hormone, cortisol, melatonin and prolactin",

abstract = "Lysine-8-vasopressin (LVP) for 10 days and in doses up to 13.5 LVP units did not significantly alter the Hamilton Depression Rating Scale scores of 12 severely depressed, treatment-resistant patients who were evaluated in a double-blind crossover study. The 24-h rhythms of melatonin, cortisol, growth hormone and prolactin appeared remarkably stable over the course of repeated measurement. LVP administration did not affect these 24-h rhythms.",

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T1 - Effect of lysine vasopressin in depressed patients on mood and 24-hour rhythm of growth hormone, cortisol, melatonin and prolactin

AU - Zohar, Joseph

AU - Drummer, Dov

AU - Edelstein, E. D.

AU - Kaiser, Nurit

AU - Belmaker, Robert H.

AU - Nir, Isaac

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Lysine-8-vasopressin (LVP) for 10 days and in doses up to 13.5 LVP units did not significantly alter the Hamilton Depression Rating Scale scores of 12 severely depressed, treatment-resistant patients who were evaluated in a double-blind crossover study. The 24-h rhythms of melatonin, cortisol, growth hormone and prolactin appeared remarkably stable over the course of repeated measurement. LVP administration did not affect these 24-h rhythms.

AB - Lysine-8-vasopressin (LVP) for 10 days and in doses up to 13.5 LVP units did not significantly alter the Hamilton Depression Rating Scale scores of 12 severely depressed, treatment-resistant patients who were evaluated in a double-blind crossover study. The 24-h rhythms of melatonin, cortisol, growth hormone and prolactin appeared remarkably stable over the course of repeated measurement. LVP administration did not affect these 24-h rhythms.

KW - 24-h rhythm

KW - Lysine vasopressin

KW - cortisol

KW - growth hormone

KW - melatonin

KW - prolactin

KW - resistant depression

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JO - Psychoneuroendocrinology

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IS - 3

ER -

Effect of lysine vasopressin in depressed patients on mood and 24-hour rhythm of growth hormone, cortisol, melatonin and prolactin

Abstract

Keywords

ASJC Scopus subject areas

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