Effect of mouse interferon on retrovirus production by chronically infected rat cells

Mahmoud Huleihel, Mordechai Aboud

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Mouse interferon (IFN) inhibited retrovirus release by both mouse and rat cells with the same efficiency. However, the antiviral state developed more slowly in rat than in mouse cells, and after removal of IFN it also persisted for a longer time in rat than in mouse cells. Under conditions where IFN strongly inhibited virus production it had no effect on cell replication nor on cellular RNA or protein synthesis.

Original languageEnglish
Pages (from-to)167-175
Number of pages9
JournalAntiviral Research
Volume2
Issue number3
DOIs
StatePublished - 1 Jan 1982

Keywords

  • interferon
  • retroviruses
  • reverse transcriptase

ASJC Scopus subject areas

  • Pharmacology
  • Virology

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