Effect of social support on psychological distress and disease activity in inflammatory bowel disease patients

Vered Slonim-Nevo, Orly Sarid, Michael Friger, Doron Schwartz, Ruslan Sergienko, Avihu Pereg, Hillel Vardi, Terri Singer, Elena Chernin, Dan Greenberg, Shmuel Odes

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Background: Psychological distress increases morbidity in ulcerative colitis (UC) and Crohnfs disease (CD). We examined whether social support is associated with distress and disease activity. Methods: There were 110 UC and 147 CD patients who completed sociodemography, economic status, disease activity (UC: Patient Simple Clinical Colitis Activity Index (P-SCCAI), CD: Patient Harvey-Bradshaw Index . (P-HBI), Multidimensional Scale of Perceived Social Support (MSPSS), Brief Symptom Inventory with Global Severity Index (GSI) of psychological distress, and 2 health-related quality-of-life scales (SF-36 Physical Health and Mental Health, and Short Inflammatory Bowel Disease Questionnaire (SIBDQ). Analysis included multiple linear regressions and structural equation modeling. Results: Disease activity was mild: UC: P-SCCAI 2.9 ± 3.5, CD: P-HBI 4.7 ± 4.7. Physical Health was better in UC 46.6 ± 11.4 versus CD 43.7 ± 10.9 (P < .02). GSI was lower in UC 0.6 ± 0.7 than CD 0.8 ± 0.7 (P = .002). MSPSS total score was equal in UC (5.9 ± 1.2) and CD (5.9 ± 1.1). MSPSS total correlated with P-SCCAI (correlation coefficient .0.240), GSI in UC (.0.470), and GSI in CD (.0.333). Economic status correlated with GSI in UC (.0.408) and CD (.0.356). MSPSS predicted GSI, Mental Health, and SIBDQ in UC and CD, and predicted P-SCCAI but not P-HBI; economic status predicted all the foregoing. Path analysis depicted GSI as mediating the effects of MSPSS and economic status on disease activity in both UC and CD. MSPSS (UC: β .0.34, CD: β .0.37) and economic status (UC: β .0.38, CD: β .0.22) reduced GSI, which then increased the disease activity (UC: β 0.56, CD: β 0.42). Conclusions: Social support and economic status are linked to UC and CD patientsf well-being. Interventions addressing these issues should be part of management.

Original languageEnglish
Pages (from-to)1389-1400
Number of pages12
JournalInflammatory Bowel Diseases
Volume24
Issue number7
DOIs
StatePublished - 8 Jun 2018

Keywords

  • Crohn's disease
  • Disease activity
  • Psychological distress
  • Social support
  • Ulcerative colitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology

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