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Effect of treatment on the global dynamics of delayed pathological angiogenesis models

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

For three different types of angiogenesis models with variable delays, we consider either continuous or impulse therapy that eradicates tumor cells and suppresses angiogenesis. For the cancer-free solution, explicit conditions of global stability for the continuous and impulsive systems are obtained, together with delay-dependent estimates for the rates of decay for the tumor volume and pathological angiogenesis.

Original languageEnglish
Pages (from-to)13-21
Number of pages9
JournalJournal of Theoretical Biology
Volume363
DOIs
StatePublished - 21 Dec 2014

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Angiogenesis
  • Global stability
  • Impulsive treatment
  • Systems of nonlinear nonautonomous delay differential equations

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics

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