TY - JOUR
T1 - Effects of a low-carbohydrate diet on weight loss and cardiometabolic profile in Chinese women
T2 - A randomised controlled feeding trial
AU - Liu, Xin
AU - Zhang, Geng
AU - Ye, Xingwang
AU - Li, Huaixing
AU - Chen, Xiafei
AU - Tang, Lixin
AU - Feng, Ying
AU - Shai, Iris
AU - Stampfer, Meir J.
AU - Hu, Frank B.
AU - Lin, Xu
N1 - Publisher Copyright:
© The Authors 2013.
PY - 2013/10/28
Y1 - 2013/10/28
N2 - Little is known about the potential adherence to and the effectiveness of a low-carbohydrate (LC) diet on weight loss and cardiometabolic risk factors in Chinese adults with a habitually high carbohydrate intake. In the present controlled feeding trial, fifty overweight or obese women (age 47.9 (SEM 0.9) years; BMI 26.7 (SEM 0.3) kg/m2) were randomly assigned to a LC non-energy-restricted diet (initial carbohydrate intake 20 g/d, with a 10 g increase weekly) or an energy-restricted (ER) diet (carbohydrate intake 156-205 g/d, ER to 5021 or 6276 kJ/d, 35% average energy reduction) for 12 weeks. Over the intervention period, the two diets had comparable compliance (96 %) and self-reported acceptability. At week 12, carbohydrate intake in the LC and ER groups contributed to 36.1 and 51.1% of total energy, respectively (P< 0.001). Although both diets showed similarly decreased mean body weight (LC -5.27 (95% CI -6.08, -4.46) kg; ER -5.09 (95% CI -5.50, -4.67) kg, P= 0.67) and percentage of fat mass measured by dual-energy X-ray absorptiometry (LC -1.19 (95% CI -1.88, -0.50) %; ER -1.56 (95% CI -2.20, -0.92) %, P= 0.42), participants in the LC group had greater reductions in the ratio of total cholesterol:HDL-cholesterol (P= 0.03) and also in the ratio of TAG:HDL-cholesterol (P= 0.01) than those in the ER group. The present 12-week diet trial suggested that both a LC non-energy-restricted diet and an ER diet were acceptable to Chinese women and both diets were equally effective in reducing weight and fat mass. Moreover, the LC diet showed beneficial effects on blood lipid profiles.
AB - Little is known about the potential adherence to and the effectiveness of a low-carbohydrate (LC) diet on weight loss and cardiometabolic risk factors in Chinese adults with a habitually high carbohydrate intake. In the present controlled feeding trial, fifty overweight or obese women (age 47.9 (SEM 0.9) years; BMI 26.7 (SEM 0.3) kg/m2) were randomly assigned to a LC non-energy-restricted diet (initial carbohydrate intake 20 g/d, with a 10 g increase weekly) or an energy-restricted (ER) diet (carbohydrate intake 156-205 g/d, ER to 5021 or 6276 kJ/d, 35% average energy reduction) for 12 weeks. Over the intervention period, the two diets had comparable compliance (96 %) and self-reported acceptability. At week 12, carbohydrate intake in the LC and ER groups contributed to 36.1 and 51.1% of total energy, respectively (P< 0.001). Although both diets showed similarly decreased mean body weight (LC -5.27 (95% CI -6.08, -4.46) kg; ER -5.09 (95% CI -5.50, -4.67) kg, P= 0.67) and percentage of fat mass measured by dual-energy X-ray absorptiometry (LC -1.19 (95% CI -1.88, -0.50) %; ER -1.56 (95% CI -2.20, -0.92) %, P= 0.42), participants in the LC group had greater reductions in the ratio of total cholesterol:HDL-cholesterol (P= 0.03) and also in the ratio of TAG:HDL-cholesterol (P= 0.01) than those in the ER group. The present 12-week diet trial suggested that both a LC non-energy-restricted diet and an ER diet were acceptable to Chinese women and both diets were equally effective in reducing weight and fat mass. Moreover, the LC diet showed beneficial effects on blood lipid profiles.
KW - Low-carbohydrate diet
KW - Obesity
KW - Overweight
KW - Randomised controlled trials
UR - http://www.scopus.com/inward/record.url?scp=84892639657&partnerID=8YFLogxK
U2 - 10.1017/S0007114513000640
DO - 10.1017/S0007114513000640
M3 - Article
C2 - 23522432
AN - SCOPUS:84892639657
SN - 0007-1145
VL - 110
SP - 1444
EP - 1453
JO - British Journal of Nutrition
JF - British Journal of Nutrition
IS - 8
ER -
