Effects of lipopolysaccharide on body temperature and plasma zinc and iron concentrations in rats exposed to different ambient temperatures

J. Kaplanski; A. Magazanik; I. Hadas; U. Sod-Moriah; V. Fraifeld

doi:10.1016/S0306-4565(99)00062-5

Effects of lipopolysaccharide on body temperature and plasma zinc and iron concentrations in rats exposed to different ambient temperatures

J. Kaplanski, A. Magazanik, I. Hadas, U. Sod-Moriah, V. Fraifeld

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Lipopolysaccharide (LPS) induced biphasic changes in body temperature (T(b)) (initial hypothermia followed by hyperthermia) in male Sprague-Dawley rats kept at 22°C, and monophasic elevation in T(b) at 34°C. LPS decreased plasma zinc (Zn) or iron (Fe) concentrations, independently of heat-induced hyperthermia or LPS-induced changes in T(b). Acute or chronic exposure of rats to high ambient temperature modifies their T(b) response to LPS, but not the effects of LPS on plasma Zn and Fe concentrations. It appears that the reduction of these elements in plasma could represent a common response to stress, including the response to endotoxin.

Original language	English
Pages (from-to)	35-38
Number of pages	4
Journal	Journal of Thermal Biology
Volume	25
Issue number	1-2
DOIs	https://doi.org/10.1016/S0306-4565(99)00062-5
State	Published - 1 Feb 2000

Keywords

Acute and chronic exposure to high ambient temperature
Acute phase responses
Body temperature
Fever
Heat-induced hyperthermia
Lipopolysaccharide
Plasma zinc and iron
Rats

ASJC Scopus subject areas

Physiology
Biochemistry
General Agricultural and Biological Sciences
Developmental Biology

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10.1016/S0306-4565(99)00062-5

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title = "Effects of lipopolysaccharide on body temperature and plasma zinc and iron concentrations in rats exposed to different ambient temperatures",

abstract = "Lipopolysaccharide (LPS) induced biphasic changes in body temperature (T(b)) (initial hypothermia followed by hyperthermia) in male Sprague-Dawley rats kept at 22°C, and monophasic elevation in T(b) at 34°C. LPS decreased plasma zinc (Zn) or iron (Fe) concentrations, independently of heat-induced hyperthermia or LPS-induced changes in T(b). Acute or chronic exposure of rats to high ambient temperature modifies their T(b) response to LPS, but not the effects of LPS on plasma Zn and Fe concentrations. It appears that the reduction of these elements in plasma could represent a common response to stress, including the response to endotoxin.",

keywords = "Acute and chronic exposure to high ambient temperature, Acute phase responses, Body temperature, Fever, Heat-induced hyperthermia, Lipopolysaccharide, Plasma zinc and iron, Rats",

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T1 - Effects of lipopolysaccharide on body temperature and plasma zinc and iron concentrations in rats exposed to different ambient temperatures

AU - Kaplanski, J.

AU - Magazanik, A.

AU - Hadas, I.

AU - Sod-Moriah, U.

AU - Fraifeld, V.

PY - 2000/2/1

Y1 - 2000/2/1

N2 - Lipopolysaccharide (LPS) induced biphasic changes in body temperature (T(b)) (initial hypothermia followed by hyperthermia) in male Sprague-Dawley rats kept at 22°C, and monophasic elevation in T(b) at 34°C. LPS decreased plasma zinc (Zn) or iron (Fe) concentrations, independently of heat-induced hyperthermia or LPS-induced changes in T(b). Acute or chronic exposure of rats to high ambient temperature modifies their T(b) response to LPS, but not the effects of LPS on plasma Zn and Fe concentrations. It appears that the reduction of these elements in plasma could represent a common response to stress, including the response to endotoxin.

AB - Lipopolysaccharide (LPS) induced biphasic changes in body temperature (T(b)) (initial hypothermia followed by hyperthermia) in male Sprague-Dawley rats kept at 22°C, and monophasic elevation in T(b) at 34°C. LPS decreased plasma zinc (Zn) or iron (Fe) concentrations, independently of heat-induced hyperthermia or LPS-induced changes in T(b). Acute or chronic exposure of rats to high ambient temperature modifies their T(b) response to LPS, but not the effects of LPS on plasma Zn and Fe concentrations. It appears that the reduction of these elements in plasma could represent a common response to stress, including the response to endotoxin.

KW - Acute and chronic exposure to high ambient temperature

KW - Acute phase responses

KW - Body temperature

KW - Fever

KW - Heat-induced hyperthermia

KW - Lipopolysaccharide

KW - Plasma zinc and iron

KW - Rats

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DO - 10.1016/S0306-4565(99)00062-5

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VL - 25

SP - 35

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JO - Journal of Thermal Biology

JF - Journal of Thermal Biology

IS - 1-2

ER -

Effects of lipopolysaccharide on body temperature and plasma zinc and iron concentrations in rats exposed to different ambient temperatures

Abstract

Keywords

ASJC Scopus subject areas

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