Effects of lithium in vitro on noradrenaline-induced cyclic AMP accumulation in rat cortical slices after reserpine-induced supersensitivity

M. E. Newman; P. Lichtenberg; R. H. Belmaker

doi:10.1016/0028-3908(85)90144-3

Effects of lithium in vitro on noradrenaline-induced cyclic AMP accumulation in rat cortical slices after reserpine-induced supersensitivity

M. E. Newman, P. Lichtenberg, R. H. Belmaker

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Lithium in vitro at concentrations of 1-2 mM and above inhibited cyclic AMP accumulation due to noradrenaline in cerebral cortical slices prepared from both control rats and rats rendered supersensitive for the noradrenaline response by intraperitoneal injection of reserpine. There was no difference in the concentration-dependence of lithium inhibition between control and reserpine-treated rats.

Original language	English
Pages (from-to)	353-355
Number of pages	3
Journal	Neuropharmacology
Volume	24
Issue number	4
DOIs	https://doi.org/10.1016/0028-3908(85)90144-3
State	Published - 1 Jan 1985
Externally published	Yes

Keywords

cyclic AMP
lithium
noradrenaline
rat brain
reserpine

ASJC Scopus subject areas

Pharmacology
Cellular and Molecular Neuroscience

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10.1016/0028-3908(85)90144-3

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abstract = "Lithium in vitro at concentrations of 1-2 mM and above inhibited cyclic AMP accumulation due to noradrenaline in cerebral cortical slices prepared from both control rats and rats rendered supersensitive for the noradrenaline response by intraperitoneal injection of reserpine. There was no difference in the concentration-dependence of lithium inhibition between control and reserpine-treated rats.",

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AU - Newman, M. E.

AU - Lichtenberg, P.

AU - Belmaker, R. H.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Lithium in vitro at concentrations of 1-2 mM and above inhibited cyclic AMP accumulation due to noradrenaline in cerebral cortical slices prepared from both control rats and rats rendered supersensitive for the noradrenaline response by intraperitoneal injection of reserpine. There was no difference in the concentration-dependence of lithium inhibition between control and reserpine-treated rats.

AB - Lithium in vitro at concentrations of 1-2 mM and above inhibited cyclic AMP accumulation due to noradrenaline in cerebral cortical slices prepared from both control rats and rats rendered supersensitive for the noradrenaline response by intraperitoneal injection of reserpine. There was no difference in the concentration-dependence of lithium inhibition between control and reserpine-treated rats.

KW - cyclic AMP

KW - lithium

KW - noradrenaline

KW - rat brain

KW - reserpine

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M3 - Article

AN - SCOPUS:0021953319

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ER -

Effects of lithium in vitro on noradrenaline-induced cyclic AMP accumulation in rat cortical slices after reserpine-induced supersensitivity

Abstract

Keywords

ASJC Scopus subject areas

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