Efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse: 12-month follow-up

Adi Y. Weintraub, Menahem Neuman, Yonatan Reuven, Joerg Neymeyer, Naama Marcus-Braun

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Objective: To evaluate the efficacy and safety of skeletonized mesh implants for advanced pelvic organ prolapse (POP). Methods: Women with advances POP underwent repair of stage III or greater anterior or posterior and apical compartment prolapse using skeletonized mesh implants (Seratom PA MR MN® system—SERAG-WIESSNER, Naila, Germany). Anatomical outcomes were assessed using pelvic organ prolapse quantification staging and functional outcomes were self-reported by the patients at 6 weeks, 6 and 12 months. Anatomical and functional cure rates, post-operative pain and dyspareunia as well as intra and post-operative complications were reported. Success was defined as a composite of no bulge symptoms and no prolapse beyond the hymenal ring. Results: At 12 months, data were available for 103 of the 105 patients originally recruited. Intra-operative complications included 2 (2 %) cases of cystotomy that were corrected vaginally. The immediate post-operative complications included 1 patient (1 %) with UTI, 4 (3.9 %) cases of self-resolved hematomas, and 6 (5.8 %) cases of bladder outlet obstruction. At 12 months, a high success rate and low complication rate was noted. Recurrence of prolapse was reported by 7 (6.6 %) patients. However, only 4 (3.8 %) underwent a repeat procedure. Two patient developed de novo SUI, and 6 (5.7 %) developed dyspareunia. No cases of mesh erosion/extrusion were noted. Conclusion: The present study showed excellent anatomical and quality of life results in patients with advanced POP treated with a skeletonized and reduced mesh system. No mesh exposure was recorded within the first year after surgery.

Original languageEnglish
Pages (from-to)1491-1498
Number of pages8
JournalWorld Journal of Urology
Volume34
Issue number10
DOIs
StatePublished - 1 Oct 2016
Externally publishedYes

Keywords

  • Mesh augmentation
  • Pelvic organ prolapse
  • Sacrospinous ligament fixation
  • Skeletonized mesh

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