Electrical conductances of dilute aqueous solutions of β-lactam antibiotics of the penicillin group in the 278.15 K to 313.15 K temperature range. Sodium salts of oxacillin, cloxacillin, dicloxacillin and nafcillin

Alexander Apelblat, Marija Bešter-Rogač

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Abstract Systematic determinations of electrical conductivities of sodium salts of semisynthetic penicillins, oxacillin, cloxacillin, dicloxacillin and nafcillin in the 278.15 K to 313.15 K temperature range are reported. These conductivities are examined by applying the Quint-Viallard conductivity equations and the Debye-Hückel equations for activity coefficients. Determined dissociation constants and the limiting conductances of involved anions are evaluated basing on the assumption that in dilute aqueous solutions these salts, similarly as sodium salts of natural penicillins, behave as acidic salts of dibasic acids which are the final products of degradation reactions in acidic media.

Original languageEnglish
Article number5011
Pages (from-to)417-424
Number of pages8
JournalJournal of Molecular Liquids
Volume211
DOIs
StatePublished - 4 Aug 2015

Keywords

  • Aqueous solutions
  • Dissociation constants
  • Electrolyte conductivity
  • Limiting ion conductances
  • Sodium cloxacillin
  • Sodium dicloxacillin
  • Sodium nafcillin
  • Sodium oxacillin

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Condensed Matter Physics
  • Spectroscopy
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Fingerprint

Dive into the research topics of 'Electrical conductances of dilute aqueous solutions of β-lactam antibiotics of the penicillin group in the 278.15 K to 313.15 K temperature range. Sodium salts of oxacillin, cloxacillin, dicloxacillin and nafcillin'. Together they form a unique fingerprint.

Cite this