Electrosensing platform for varenicline based on reduced graphene oxide

Nagappa L. Teradal; S Narayan Prashanth S Narayan; Jaldappagari Seetharamappa; Ashis K. Satpati

doi:10.1002/elan.201400226

Electrosensing platform for varenicline based on reduced graphene oxide

Nagappa L. Teradal, S Narayan Prashanth S Narayan, Jaldappagari Seetharamappa, Ashis K. Satpati

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Graphene oxide (GO) was synthesized and reduced by chemical, hydrothermal and electrochemical methods. The GO and reduced GO was characterized by XRD, FTIR, absorption, Raman, FESEM and AFM methods. Chemically reduced GO (CrGO) was observed to efficiently enhance the electron transfer kinetics of varenicline compared to hydrothermally and electrochemically reduced GO. Hence, CrGO was used for the fabrication of an electrochemical sensor for the determination of varenicline in the concentration range of 0.03-50 μM with a limit of detection of 7.03 nM. The applicability of the proposed sensor was demonstrated by analyzing the biological samples containing varenicline.

Original language	English
Pages (from-to)	2173-2181
Number of pages	9
Journal	Electroanalysis
Volume	26
Issue number	10
DOIs	https://doi.org/10.1002/elan.201400226
State	Published - 1 Oct 2014
Externally published	Yes

Keywords

Biological samples
Chemically reduced graphene oxide
Varenicline

ASJC Scopus subject areas

Analytical Chemistry
Electrochemistry

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10.1002/elan.201400226

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title = "Electrosensing platform for varenicline based on reduced graphene oxide",

abstract = "Graphene oxide (GO) was synthesized and reduced by chemical, hydrothermal and electrochemical methods. The GO and reduced GO was characterized by XRD, FTIR, absorption, Raman, FESEM and AFM methods. Chemically reduced GO (CrGO) was observed to efficiently enhance the electron transfer kinetics of varenicline compared to hydrothermally and electrochemically reduced GO. Hence, CrGO was used for the fabrication of an electrochemical sensor for the determination of varenicline in the concentration range of 0.03-50 μM with a limit of detection of 7.03 nM. The applicability of the proposed sensor was demonstrated by analyzing the biological samples containing varenicline.",

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author = "Teradal, {Nagappa L.} and {Prashanth S Narayan}, {S Narayan} and Jaldappagari Seetharamappa and Satpati, {Ashis K.}",

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T1 - Electrosensing platform for varenicline based on reduced graphene oxide

AU - Teradal, Nagappa L.

AU - Prashanth S Narayan, S Narayan

AU - Seetharamappa, Jaldappagari

AU - Satpati, Ashis K.

PY - 2014/10/1

Y1 - 2014/10/1

N2 - Graphene oxide (GO) was synthesized and reduced by chemical, hydrothermal and electrochemical methods. The GO and reduced GO was characterized by XRD, FTIR, absorption, Raman, FESEM and AFM methods. Chemically reduced GO (CrGO) was observed to efficiently enhance the electron transfer kinetics of varenicline compared to hydrothermally and electrochemically reduced GO. Hence, CrGO was used for the fabrication of an electrochemical sensor for the determination of varenicline in the concentration range of 0.03-50 μM with a limit of detection of 7.03 nM. The applicability of the proposed sensor was demonstrated by analyzing the biological samples containing varenicline.

AB - Graphene oxide (GO) was synthesized and reduced by chemical, hydrothermal and electrochemical methods. The GO and reduced GO was characterized by XRD, FTIR, absorption, Raman, FESEM and AFM methods. Chemically reduced GO (CrGO) was observed to efficiently enhance the electron transfer kinetics of varenicline compared to hydrothermally and electrochemically reduced GO. Hence, CrGO was used for the fabrication of an electrochemical sensor for the determination of varenicline in the concentration range of 0.03-50 μM with a limit of detection of 7.03 nM. The applicability of the proposed sensor was demonstrated by analyzing the biological samples containing varenicline.

KW - Biological samples

KW - Chemically reduced graphene oxide

KW - Varenicline

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JO - Electroanalysis

JF - Electroanalysis

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Electrosensing platform for varenicline based on reduced graphene oxide

Abstract

Keywords

ASJC Scopus subject areas

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