Electrostatic Limit of Detection of Nanowire-Based Sensors

Alex Henning, Michel Molotskii, Nandhini Swaminathan, Yonathan Vaknin, Andrey Godkin, Gil Shalev, Yossi Rosenwaks

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Scanning gate microscopy is used to determine the electrostatic limit of detection (LOD) of a nanowire (NW) based chemical sensor with a precision of sub-elementary charge. The presented method is validated with an electrostatically formed NW whose active area and shape are tunable by biasing a multiple gate field-effect transistor (FET). By using the tip of an atomic force microscope (AFM) as a local top gate, the field effect of adsorbed molecules is emulated. The tip induced charge is quantified with an analytical electrostatic model and it is shown that the NW sensor is sensitive to about an elementary charge and that the measurements with the AFM tip are in agreement with sensing of ethanol vapor. This method is applicable to any FET-based chemical and biological sensor, provides a means to predict the absolute sensor performance limit, and suggests a standardized way to compare LODs and sensitivities of various sensors. Scanning gate microscopy is used in combination with an analytical model to determine the electrostatic limit of detection of nanowire-based chemical sensors. An electrostatic limit of detection of a single elementary charge is determined for an electrostatically formed nanowire with tunable diameter. The employed method provides a standard way to evaluate field-effect transistor based chemical sensors.

Original languageEnglish
Pages (from-to)4931-4937
Number of pages7
Issue number37
StatePublished - 1 Oct 2015
Externally publishedYes


  • Kelvin probe force microscopy
  • Si nanowires
  • limit of detection
  • multiple gate transistors
  • scanning gate microscopy
  • sensors

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry (all)
  • Materials Science (all)


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