Objective. To evaluate serum levels of hyaluronic acid (HA) in patients with fibromyalgia (FM). Methods. HA serum levels were evaluated by a radiometric assay in 42 women with FM (ACR criteria), 27 female patients with rheumatoid arthritis (RA) and 36 healthy female controls matched for age. Results. HA serum levels (mean μg/l ± SEM) were 41 ± 8.7 in healthy controls; 113 ± 15.9 in RA; and 420 ± 26 in FM. Conclusion. HA serum levels in women with FM were significantly elevated compared to healthy controls and patients with RA. This observation suggests that FM is associated with a biochemical abnormality and that serum HA could be a laboratory marker for its diagnosis.
|Number of pages||4|
|Journal||Journal of Rheumatology|
|State||Published - 1 Nov 1997|
- Hyaluronic acid
ASJC Scopus subject areas
- Immunology and Allergy