Elevated morbidity and health care use in children with obstructive sleep apnea syndrome

Ariel Tarasiuk, Sari Greenberg-Dotan, Tzahit Simon-Tuval, Bruria Freidman, Aviv D. Goldbart, Asher Tal, Haim Reuveni

Research output: Contribution to journalReview articlepeer-review

137 Scopus citations


Rationale: Health care use, a reliable measure of morbidity, is noticeably higher 1 yr before obstructive sleep apnea syndrome (OSAS) diagnosis in preschool children. It is not clear at what age OSAS-related morbidity becomes expressed. Objective: To explore morbidity and health care use among children with OSAS starting from first year of life. Methods: Case-control study, starting from the first year of life to date of OSAS diagnosis, among 156 patients (age range, 3-5 yr) and their pair-matched healthy control subjects, by age, sex, primary care physician, and geographic location. Measurements: Patients with OSAS underwent nocturnal polysomnography studies. Medical records during hospital visits were reviewed for diagnosis. Variables of health care use were obtained from computerized databases of Clalit Health Care Services, the largest health maintenance organization in Israel. Main Results: From the first year of life to date of OSAS diagnosis, children with OSAS had 40% more (p = 0.048) hospital visits, 20% more repeated (two or more) visits (p < 0.0001), and higher consumption of antiinfective and respiratory system drugs (p < 0.0001). Referrals of children with OSAS to otolaryngology surgeons and pediatric pulmonologists were higher from Year 1 (p < 0.0001) to date of OSAS diagnosis, especially in Year 4 (odds ratio, 9.4; 95% confidence interval, 4.2-21.1). The 215% elevation (p < 0.0001) in health care use of the OSAS group was due mainly to higher occurrence of respiratory tract morbidity (p < 0.0001). Conclusions: Practitioners should be aware that starting in Year 1 until date of diagnosis, children with OSAS have higher health care use, mostly related to respiratory diseases.

Original languageEnglish
Pages (from-to)55-61
Number of pages7
JournalAmerican Journal of Respiratory and Critical Care Medicine
Issue number1
StatePublished - 1 Jan 2007


  • Children
  • Heath care use
  • Obstructive sleep apnea syndrome
  • Respiratory tract morbidity

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine


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