Enantioselective oxidation of 2-methyl-1-butanol by alcohol oxidase from methylotrophic yeasts

Dawn S. Clark, Shimona Geresh, Robert Di Cosimo

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The oxidation of racemic 2-methyl-1-butanol by the soluble alcohol oxidase from Candida boidinii produced an enantiomeric excess of (R)-2-methyl-1-butanol (E = 1.65) as the reaction progressed. This degree of enantioselectivity was not observed with alcohol oxidase isolated from either Hansenula sp. or Pichia pastoris.

Original languageEnglish
Pages (from-to)1745-1748
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume4
Issue number14
DOIs
StatePublished - 21 Jul 1994
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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