Endophytic bacteria as a source of bioactive compounds

R. Monika, Rajesh Kumar Singh, Ankita Shrivastava, Arpana Yadav, Akhileshwar Kumar Srivastava

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations


The interactions between plants and microbes produce various kinds of secondary metabolites. The specific genes of bacterial cells living inside plant tissues as endophytes attribute to the production and transformation of small molecules into bioactive compounds. Researches on antibiotics and microbial natural products explain the potential of the fight against the increasing issue of antibiotic resistance. Therefore, it is required to explore new bioactive compounds to tackle such problems. The use of the medicinal plant as traditional medicine is as old as mankind and believed that all types of plant species have endophytic bacteria (EB). The natural compounds produced by EB have multiple potential applications in the medical field. The EB produce several natural products like Ecomycins, Munumbicins, and Xiamycins are antibacterial, antimycotic, and antiplasmodial. Some of these natural products possess antiviral properties (Human Immunodeficiency Virus (HIV)) properties. This book chapter deals with the significance of the natural product of EB in disease treatments.

Original languageEnglish
Title of host publicationMicrobial Endophytes
Subtitle of host publicationProspects for Sustainable Agriculture
Number of pages14
ISBN (Print)9780128187340
StatePublished - 17 Sep 2019
Externally publishedYes


  • Antibiotics
  • Bioactive compounds
  • Drug-resistance
  • Endophytic bacteria

ASJC Scopus subject areas

  • Engineering (all)
  • Agricultural and Biological Sciences (all)


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