Enzymatic activity of glycogen metabolism in chorionic villi

M. Chowers, D. Abeliovich, R. Potashnik, N. Bashan

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Glycogen content and six major enzymatic activities involved in glycogen metabolism were analysed in chorionic villi (CV). Glycogen levels were found to be lower than those known to exist in liver and muscle. Activities of α-glucosidase, amylo-1,6-glucosidase, phosphorylase b and phosphorylase kinase were detectable by standard methods. The enzymatic activities of glucose-6-phosphatase in phosphorylase a were undetectable. These findings suggest that CV biopsies can be useful for first-trimester diagnosis of glycogen storage disease types II, III and VI, but not for type I (glucose-6-phosphatase deficiency).

Original languageEnglish
Pages (from-to)505-509
Number of pages5
Issue number6
StatePublished - 1 Jan 1986

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Developmental Biology


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