Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Thao M. Xiong; Edzna S. Garcia; Junfeng Chen; Lingyang Zhu; Ariale J. Alzona; Steven C. Zimmerman

doi:10.1039/d1cc05578j

Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Thao M. Xiong, Edzna S. Garcia, Junfeng Chen, Lingyang Zhu, Ariale J. Alzona, Steven C. Zimmerman

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst "cofactors"and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.

Original language	English
Pages (from-to)	985-988
Number of pages	4
Journal	Chemical Communications
Volume	58
Issue number	7
DOIs	https://doi.org/10.1039/d1cc05578j
State	Published - 21 Jan 2022
Externally published	Yes

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
General Chemistry
Catalysis

Access to Document

10.1039/d1cc05578j

Cite this

@article{04438bbdb8e54cebb402f3b732a5d0de,

title = "Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors",

abstract = "We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst {"}cofactors{"}and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.",

author = "Xiong, {Thao M.} and Garcia, {Edzna S.} and Junfeng Chen and Lingyang Zhu and Alzona, {Ariale J.} and Zimmerman, {Steven C.}",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",

year = "2022",

month = jan,

day = "21",

doi = "10.1039/d1cc05578j",

language = "English",

volume = "58",

pages = "985--988",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "7",

}

TY - JOUR

T1 - Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

AU - Xiong, Thao M.

AU - Garcia, Edzna S.

AU - Chen, Junfeng

AU - Zhu, Lingyang

AU - Alzona, Ariale J.

AU - Zimmerman, Steven C.

PY - 2022/1/21

Y1 - 2022/1/21

N2 - We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst "cofactors"and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.

AB - We report a modular approach in which a noncovalently cross-linked single chain nanoparticle (SCNP) selectively binds catalyst "cofactors"and substrates to increase both the catalytic activity of a Cu-catalyzed alkyne-azide cycloaddition reaction and the Ru-catalyzed cleavage of allylcarbamate groups compared to the free catalysts.

UR - http://www.scopus.com/inward/record.url?scp=85123359399&partnerID=8YFLogxK

U2 - 10.1039/d1cc05578j

DO - 10.1039/d1cc05578j

M3 - Article

C2 - 34935784

AN - SCOPUS:85123359399

SN - 1359-7345

VL - 58

SP - 985

EP - 988

JO - Chemical Communications

JF - Chemical Communications

IS - 7

ER -

Enzyme-like catalysis by single chain nanoparticles that use transition metal cofactors

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this