Epithelial ovarian tumors of borderline malignancy: A study of 50 cases

B. Piura, I. Blickstein

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Piura B, Dgani R, Blickstein I, Yanai-Inbar I, Czernobilsky B, Glezerman M. Epithelial ovarian tumors of borderline malignancy: A study of 50 cases. Int J Gynecol Cancer 1992; 2: 189-197. Of 50 patients with borderline epithelial ovarian tumors, 32 (64%) had serous, 17 (34%) had mucinous and one (2%) had endometrioid tumor. All patients with mucinous tumor had stage I disease, whereas 4 patients with serous tumor had stage II-III disease. Five patients (10%) were pregnant at the time of diagnosis. Seventeen patients (34%) had initial surgery with ovarian conservation and 7 of them were not subjected to further surgery. Five patients (10%) received adjuvant chemotherapy. Five-year survival and 5-year disease-free survival rates were 100% and 96.4%, respectively. It is concluded that for patients with stage IA disease unilateral salpingo-oophorectomy seems to be adequate treatment and for those with more than stage IA disease, surgery should include total abdominal hysterectomy and bilateral salpingo-oophorectomy. Although the effectiveness of chemotherapy in these tumors is uncertain, adjuvant chemotherapy is advocated for patients in whom spread of the tumor beyond the ovaries has occurred.

Original languageEnglish
Pages (from-to)189-197
Number of pages9
JournalInternational Journal of Gynecological Cancer
Issue number4
StatePublished - 1 Jan 1992


  • Adjuvant chemotherapy
  • Borderline malignancy
  • Conservative surgery
  • Epithelial ovarian tumors
  • Low malignancy potential


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