Erythrocyte glutathione peroxidase activity in asthmatic children

H. Bibi, M. Schlesinger, E. Tabachnik, Y. Schwartz, H. Iscovitz, A. Iaina

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Erythrocyte glutathione peroxidase (GPX) levels were determined in 56 asthmatic children. Lowest levels were found during acute asthmatic attack (13.53 ± 2.94 IU) which were significantly less than controls (20.4 ± 5.44 IU) (P < .001). Post-attack levels 1 week later rose significantly (16.77 ± 2.63 IU), but were still less than normal values (P = .001). GPX levels (16.96 ± 3.28 IU) were less than controls (P < .03) even in patients with mild symptomatology. Asymptomatic patients receiving theophylline had normal levels. Low GPX activity in asthmatic patients may play a role in the pathogenesis of the disease.

Original languageEnglish
Pages (from-to)339-340
Number of pages2
JournalAnnals of Allergy
Volume61
Issue number5
StatePublished - 1 Dec 1988
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy

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