Abstract
Erythrocyte glutathione peroxidase (GPX) levels were determined in 56 asthmatic children. Lowest levels were found during acute asthmatic attack (13.53 ± 2.94 IU) which were significantly less than controls (20.4 ± 5.44 IU) (P < .001). Post-attack levels 1 week later rose significantly (16.77 ± 2.63 IU), but were still less than normal values (P = .001). GPX levels (16.96 ± 3.28 IU) were less than controls (P < .03) even in patients with mild symptomatology. Asymptomatic patients receiving theophylline had normal levels. Low GPX activity in asthmatic patients may play a role in the pathogenesis of the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 339-340 |
| Number of pages | 2 |
| Journal | Annals of Allergy |
| Volume | 61 |
| Issue number | 5 |
| State | Published - 1 Dec 1988 |
ASJC Scopus subject areas
- Immunology and Allergy