Estrogen-progestin therapy and coronary heart disease in radiation-induced rectal telangiectases

Yaron Niv, Yaakov Henkin

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We describe two elderly men with preexisting coronary heart disease (CHD) and prostatic carcinoma who presented with intractable anemia due to radiation-induced rectal telangiectases and bleeding. Remission of the bleeding was achieved in both patients by treatment with an estrogen-progestin preparation. However, aggravation of the CHD occurred in both patients. We believe that estrogen-progestin preparations have a potential in the treatment of men with radiation-induced rectal telangiectases, but additional studies are needed to evaluate their long-term effects and optimal dose.

Original languageEnglish
Pages (from-to)295-297
Number of pages3
JournalJournal of Clinical Gastroenterology
Volume21
Issue number4
DOIs
StatePublished - 1 Jan 1995

Keywords

  • Coronary heart disease
  • Estrogens
  • Progestins
  • Radiation
  • Rectal telangiectases

ASJC Scopus subject areas

  • Gastroenterology

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