Estrogen-progestin therapy and coronary heart disease in radiation-induced rectal telangiectases

Yaron Niv, Yaakov Henkin

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations

    Abstract

    We describe two elderly men with preexisting coronary heart disease (CHD) and prostatic carcinoma who presented with intractable anemia due to radiation-induced rectal telangiectases and bleeding. Remission of the bleeding was achieved in both patients by treatment with an estrogen-progestin preparation. However, aggravation of the CHD occurred in both patients. We believe that estrogen-progestin preparations have a potential in the treatment of men with radiation-induced rectal telangiectases, but additional studies are needed to evaluate their long-term effects and optimal dose.

    Original languageEnglish
    Pages (from-to)295-297
    Number of pages3
    JournalJournal of Clinical Gastroenterology
    Volume21
    Issue number4
    DOIs
    StatePublished - 1 Jan 1995

    Keywords

    • Coronary heart disease
    • Estrogens
    • Progestins
    • Radiation
    • Rectal telangiectases

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