TY - JOUR
T1 - Ethnicity Affects A1C Levels in Patients With Diagnosed Type 2 Diabetes in Southern Israel
AU - Treister-Goltzman, Yulia
AU - Liberty, Idit F.
AU - Peleg, Roni
N1 - Publisher Copyright:
© 2023 by the American Diabetes Association.
PY - 2024/12/1
Y1 - 2024/12/1
N2 - PURPOSE | To assess whether ethnicity affects the association between A1C and fasting glucose in people with type 2 diabetes. METHODS | This investigation was an epidemiological, cross-sectional study based on computerized medical records of the Southern District of Clalit Health Services. The study population comprised patients $40 years of age with type 2 diabetes who underwent blood tests between 8 August 2015 and 20 July 2020. A normal-error multiple linear regression model was used to assess differences in associations among ethnic groups (i.e., Arabs, Ethiopian Jews, and non-Ethiopian Jews) and A1C. RESULTS | A total of 59,432 patients with type 2 diabetes were included in the study. Of these, 1,804 were Jews of Ethiopian origin, 49,296 were non-Ethiopian Jews, and 8,332 were Arabs. Compared with non-Ethiopian Jews, A1C levels were increased by 0.1% (1 mmol/mol) among Ethiopian Jews and by 0.3% (3 mmol/mol) among Arabs. Ethnicity was a strong predictor of A1C, explaining 0.6% of its variance. An A1C level of 7% (53 mmol/mol) correlated with fasting glucose levels of 141, 136, and 126 mg/dL in non-Ethiopian Jews, Ethiopian Jews, and Arabs, respectively. CONCLUSION | Ethnic differences in A1C should be considered by clinicians, researchers, and policymakers.
AB - PURPOSE | To assess whether ethnicity affects the association between A1C and fasting glucose in people with type 2 diabetes. METHODS | This investigation was an epidemiological, cross-sectional study based on computerized medical records of the Southern District of Clalit Health Services. The study population comprised patients $40 years of age with type 2 diabetes who underwent blood tests between 8 August 2015 and 20 July 2020. A normal-error multiple linear regression model was used to assess differences in associations among ethnic groups (i.e., Arabs, Ethiopian Jews, and non-Ethiopian Jews) and A1C. RESULTS | A total of 59,432 patients with type 2 diabetes were included in the study. Of these, 1,804 were Jews of Ethiopian origin, 49,296 were non-Ethiopian Jews, and 8,332 were Arabs. Compared with non-Ethiopian Jews, A1C levels were increased by 0.1% (1 mmol/mol) among Ethiopian Jews and by 0.3% (3 mmol/mol) among Arabs. Ethnicity was a strong predictor of A1C, explaining 0.6% of its variance. An A1C level of 7% (53 mmol/mol) correlated with fasting glucose levels of 141, 136, and 126 mg/dL in non-Ethiopian Jews, Ethiopian Jews, and Arabs, respectively. CONCLUSION | Ethnic differences in A1C should be considered by clinicians, researchers, and policymakers.
UR - http://www.scopus.com/inward/record.url?scp=85185690423&partnerID=8YFLogxK
U2 - 10.2337/ds23-0009
DO - 10.2337/ds23-0009
M3 - Article
C2 - 38385090
AN - SCOPUS:85185690423
SN - 1040-9165
VL - 37
SP - 86
EP - 94
JO - Diabetes Spectrum
JF - Diabetes Spectrum
IS - 1
ER -