Ethnicity Affects A1C Levels in Patients With Diagnosed Type 2 Diabetes in Southern Israel

Yulia Treister-Goltzman, Idit F. Liberty, Roni Peleg

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

PURPOSE | To assess whether ethnicity affects the association between A1C and fasting glucose in people with type 2 diabetes. METHODS | This investigation was an epidemiological, cross-sectional study based on computerized medical records of the Southern District of Clalit Health Services. The study population comprised patients $40 years of age with type 2 diabetes who underwent blood tests between 8 August 2015 and 20 July 2020. A normal-error multiple linear regression model was used to assess differences in associations among ethnic groups (i.e., Arabs, Ethiopian Jews, and non-Ethiopian Jews) and A1C. RESULTS | A total of 59,432 patients with type 2 diabetes were included in the study. Of these, 1,804 were Jews of Ethiopian origin, 49,296 were non-Ethiopian Jews, and 8,332 were Arabs. Compared with non-Ethiopian Jews, A1C levels were increased by 0.1% (1 mmol/mol) among Ethiopian Jews and by 0.3% (3 mmol/mol) among Arabs. Ethnicity was a strong predictor of A1C, explaining 0.6% of its variance. An A1C level of 7% (53 mmol/mol) correlated with fasting glucose levels of 141, 136, and 126 mg/dL in non-Ethiopian Jews, Ethiopian Jews, and Arabs, respectively. CONCLUSION | Ethnic differences in A1C should be considered by clinicians, researchers, and policymakers.

Original languageEnglish
Pages (from-to)86-94
Number of pages9
JournalDiabetes Spectrum
Volume37
Issue number1
DOIs
StatePublished - 1 Dec 2024

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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