Evolution in microfluidic droplet

Itay Levin, Amir Aharoni

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations


High-throughput screening (HTS) of enzymatic activity is important for directed evolution-based enzyme engineering. However, substrate and product diffusion can severely compromise these HTS assays. In this issue of Chemistry & Biology, Kintses and coworkers describe a microfluidic platform for the directed evolution of enzymes in droplets that allows for the screening of 10 7 mutants per round of evolution.

Original languageEnglish
Pages (from-to)929-931
Number of pages3
JournalChemistry and Biology
Issue number8
StatePublished - 24 Aug 2012

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


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