Evolution in microfluidic droplet

Itay Levin, Amir Aharoni

Research output: Contribution to journalShort surveypeer-review

8 Scopus citations

Abstract

High-throughput screening (HTS) of enzymatic activity is important for directed evolution-based enzyme engineering. However, substrate and product diffusion can severely compromise these HTS assays. In this issue of Chemistry & Biology, Kintses and coworkers describe a microfluidic platform for the directed evolution of enzymes in droplets that allows for the screening of 10 7 mutants per round of evolution.

Original languageEnglish
Pages (from-to)929-931
Number of pages3
JournalChemistry and Biology
Volume19
Issue number8
DOIs
StatePublished - 24 Aug 2012

Fingerprint

Dive into the research topics of 'Evolution in microfluidic droplet'. Together they form a unique fingerprint.

Cite this