Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells

Sumit Mukherjee, Milana Frenkel-Morgenstern

Research output: Contribution to journalShort surveypeer-review

10 Scopus citations

Abstract

Chimeric RNAs are generated by the fusion of the exons or introns of two genes. The generation of chimeric RNAs is important for the functional expansion of cells. Here, we describe the functional implications of chimeric RNAs for generating phenotypic plasticity from an evolutionary perspective.

Original languageEnglish
Pages (from-to)4-7
Number of pages4
JournalTrends in Genetics
Volume38
Issue number1
DOIs
StatePublished - 1 Jan 2022
Externally publishedYes

Keywords

  • cancer evolution
  • chimeric RNA
  • gene fusion
  • phenotypic plasticity

ASJC Scopus subject areas

  • Genetics

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