Examining the Temporal Association between Substance Abuse/Dependence and Mania in Older Adults

S Canham, C Kaufmann, C Ramsey, AP Spira, N O'Rourke

Research output: Contribution to journalMeeting Abstract

Abstract

Comorbid mania and substance abuse/dependence is an increasing
public health concern among older adults, though the temporal relationship between them is unclear. We studied 13,489 participants aged
≥50 years at Wave 1 (W1: 2001-2002) and Wave 2 (W2: 2004-2005)
of the National Epidemiologic Survey on Alcohol and Related Conditions. We examined whether lifetime mania at W1 predicted incident
alcohol or drug abuse/dependence by W2; and whether lifetime alcohol or drug abuse/dependence at W1 predicted incident manic episode
by W2. At W1, 276 adults had mania; at W2, 132 adults had an incident manic episode. Older adults with lifetime alcohol abuse/dependence at W1 had an elevated risk of incident manic episodes (adjusted
odds ratio=2.11, 95% confidence interval=1.19-3.75, p=0.011); there
was no association between lifetime mania at W1 and incident substance
abuse/dependence at W2. Because substance abuse complicates remission from mania, attention to older adults with substance abuse/dependence histories is needed.
Original languageEnglish
Pages (from-to)29-29
Number of pages1
JournalThe Gerontologist
Volume53
Issue numberS1
DOIs
StatePublished - Nov 2013

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