Exposure to traffic noise and ambient air pollution and the risk for preeclampsia

Natalya Bilenko, Michal Ashin, Michael Friger, Ruslan Sergienko, Eyal Sheiner

Research output: Contribution to journalMeeting Abstractpeer-review


Traffic noise and ambient air pollution might have a significant impact on public health. A limited number of studies have examined the association between traffic noise or ambient air pollution and preeclampsia. The study was aimed to examine whether traffic-related noise and air pollution are associated with the incidence of preeclampsia.
Study Design
In this prospective study, we interviewed pregnant women who were enrolled to Maternal and Child Health Clinics between the years 2013-2016. The questionnaire consisted of personal and health information as well as a self-assessment survey regarding exposure to home traffic noise. Follow-up was performed until delivery. Data on blood pressure levels and additional measurements during the pregnancy were recorded from the hospital files. Environmental noise was measured using a portable dosimeter, and the traffic-related air pollution level was calculated using the AERMOD pollutant dispersion model. The impact of traffic-related air pollution on birth outcomes was examined using a linear multi-variable analysis.
During the study period, 285 pregnant women were enrolled. A significant correlation was noted between measured and self-reported noise (R= 0.214; P=0.001). Reported traffic noise (on a scale of 0-10) was significantly higher in patients who subsequently develop preeclampsia (6.4+/- 2.4 vs. 4.8+/- 2.9; P=0.014), and a level of ≥6 was noted as a risk factor for the development of preeclampsia (OR=1.13; 95% CI 1.1-1.2). Using a multiple logistic regression model, controlling for confounders such as BMI, parity, maternal age and chronic maternal diseases, traffic-related noise was noted as an independent risk factor for preeclampsia (adjusted OR=1.2, 95% CI 1.1-1.4; P=0.037). Likewise, elevated nitrogen oxide concentration was noted as an independent risk factor for preeclampsia in another multivariable model, (adjusted OR=1.2, 95% CI 1.1-1.5; P=0.028). Combined exposure to traffic noise and air pollution increased the risk for preeclampsia, with an OR of 5.4 (95%CI 1.8-16.1; P=0.003).
Traffic-related noise and ambient air pollution are independent risk factors for the development of preeclampsia.
Original languageEnglish GB
Pages (from-to)S192-S192
JournalAmerican Journal of Obstetrics and Gynecology
Issue number1
StatePublished - Jan 2018


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