Fabrication of an electrochemical sensor based on multiwalled carbon nanotubes for almotriptan

Prashanth S. Narayan, Nagappa L. Teradal, Shankara S. Kalanur, J. Seetharamappa

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

In the present work, the electrochemical behavior of an antimigraine drug, almotriptan malate (ALM), on a multiwalled carbon nanotube (MWCNT) film modified glassy carbon electrode under cyclic voltammetry was described for the first time. A significant enhancement in the oxidation peak current of ALM was noticed at MWCNT-GCE. This property was exploited to develop a simple, sensitive and time-saving differential pulse voltammetric method for the determination of ALM in bulk and pharmaceutical samples. A linear relationship was observed between concentration and peak current with a correlation coefficient of 0.9915 in the range of 0.25-37.5μM ALM.

Original languageEnglish
Pages (from-to)2684-2690
Number of pages7
JournalElectroanalysis
Volume25
Issue number12
DOIs
StatePublished - 1 Jan 2013
Externally publishedYes

Keywords

  • Almotriptan
  • Electrochemical sensors
  • Modified electrodes
  • Multiwalled carbon nanotubes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

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