Facile acetal dynamic combinatorial library

Dvora Berkovich-Berger, N. Gabriel Lemcoff

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

We herein report our first results on the use of simple acetalation chemistry in the service of dynamic combinatorial libraries (DCLs); the reaction between triethylene glycol and 4-nitrobenzaldehyde afforded a DCL of more than 15 cyclic and acyclic species; all of which were separated and characterized; the smaller macrocyclic compounds were successfully amplified by the use of ammonium ions.

Original languageEnglish
Pages (from-to)1686-1688
Number of pages3
JournalChemical Communications
Issue number14
DOIs
StatePublished - 1 Jan 2008

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