TY - JOUR
T1 - Fatal paraphenylenediamine (hair dye) intoxication in a child resembling ludwig's angina
AU - Lifshits, Matitiahu
AU - Yagupsky, Pablo
AU - Sofer, Shaul
PY - 1993/1/1
Y1 - 1993/1/1
N2 - A 6 year-old child with paraphenylenediamine intoxication is presented. The patient suffered from sore throat, cough, and anorexia, followed by severe dyspnea caused by edema of the tongue, pharynx, and neck, renal failure, and metabolic acidosis. A presumptive diagnosis of Ludwig's angina, a severe anaerobic infection of the sublingual neck space, was entertained. Despite institution of vigorous supportive therapy and administration of antibiotics, the child developed irreversible ventricular fibrillation and died eight hours after admission. Two days after the patient's death, his father recalled that the child and his dog ingested an unidentified substance shortly before the onset of the child's symptoms. The dog died within a few hours. The substance was identified as the hair dye, paraphenylenediamine.
AB - A 6 year-old child with paraphenylenediamine intoxication is presented. The patient suffered from sore throat, cough, and anorexia, followed by severe dyspnea caused by edema of the tongue, pharynx, and neck, renal failure, and metabolic acidosis. A presumptive diagnosis of Ludwig's angina, a severe anaerobic infection of the sublingual neck space, was entertained. Despite institution of vigorous supportive therapy and administration of antibiotics, the child developed irreversible ventricular fibrillation and died eight hours after admission. Two days after the patient's death, his father recalled that the child and his dog ingested an unidentified substance shortly before the onset of the child's symptoms. The dog died within a few hours. The substance was identified as the hair dye, paraphenylenediamine.
KW - Fatality
KW - Intoxication
KW - Paraphenylenediamine
KW - Soft tissue edema
UR - http://www.scopus.com/inward/record.url?scp=0027739334&partnerID=8YFLogxK
U2 - 10.3109/15563659309025769
DO - 10.3109/15563659309025769
M3 - Comment/debate
AN - SCOPUS:0027739334
SN - 1556-3650
VL - 31
SP - 653
EP - 656
JO - Clinical Toxicology
JF - Clinical Toxicology
IS - 4
ER -