Fear generalization in the primate amygdala

Jennifer Resnik, Rony Paz

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Broad generalization of negative memories is a potential etiology for anxiety disorders, yet the underlying mechanisms remain unknown. We developed a non-human primate model that replicates behavioral observations in humans and identifies specific changes in tuning properties of amygdala neurons: the width of auditory tuning increases with the distance of its center from the conditioned stimulus. This center-width relationship can account for better detection and at the same time explain the wide stimulus generalization.

Original languageEnglish
Pages (from-to)188-190
JournalNature Neuroscience
Issue number2
StatePublished - 17 Feb 2015
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience (all)


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